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User Documentation BioSpec/PharmaScan with AVANCE NEO, V004SearchContentsHome
 
 
Animal Body Temperature Conditioning "Air"
 
Prerequisites
Body Temperature Conditioning System (option) installed.
Air Supply & Gas Removal Pump    (option) installed.
 
Functionality
The warm water based Body Temperature Conditioning System creates the warm water which is routed via hoses to the instrument and circulates in the Animal Cell Extension (ACE) located just prior to the connector for the animal cradle. A water/air heat exchanger is also located in the ACE.
Warm air is created by the Air Circulation option that pumps air through the heat exchanger in the ACE and via the cradle connector into the animal cassette.
Within the animal cassette, a diffusor hose is used to transport and deliver the air stream to the location of the animal.
Air suction is located in the rear of the animal cassette (see cradle interface description) so that a closed loop of air circulation can be maintained with this setup. A portion of the circulating air flow can be redirected to an isoflurane adsorber (see schematics). Typical amount is about 2 liter per minute (lpm). It can be regulated at the valve at the air circulation system.
 
Schematics of Air Circulation
Sketch showing the Air Circulation System (Option Air Supply & Gas Removal Pump). It consists of a diaphragm pump, corresponding hoses, adjustable flow valves with meters for both, the closed air flow circuit to the animal chamber and the extraction pathway to an activated charcoal container *. The air flow to the animal cassette can be regulated from 0 to 20 lpm and the flow to the activated charcoal canister from 0 to 5 lpm.
 
Recommended Settings
A water bath temperature of about 60 deg. Celsius in combination with an air flow of about 10 liter per minute (lpm) results typically in a temperature required for animal temperature stabilization. Tip: More air flow will transport more heat and will be more efficient than increasing the water bath temperature.