Category Archives: Methods & Applications

Posts describing the use of the nmr spectroscopy (MRS) methodology, either from a practical point of view (how to perform certain experiment), or from a more theoretical perspective (description of techniques and their application).

Fast 1D long-range proton-proton correlations

Methods & Applications, Our Publications, ,

“Selective 1D HCH experiment: a fast NMR tool that connect protons belonging to different spin systems”, by Sergi Gil, Juan Félix Espinosa and Teodor Parella; Magnetic Resonance in Chemistry 49, 301-306 (2011). DOI: 10.1002/mrc.2744

A selective 1D version of the HCH experiment (selHCH) is proposed for the efficient and fast correlation between protons belonging to different spin systems. The experiment consists of two consecutive, doubly selective heteronuclear JCH transfer steps that can individually be optimized. As any conventional proton-selective 1D experiment, the successful application of a frequency-selective 180° pulse on a well-isolated proton is the only practical requirement. Continue reading Fast 1D long-range proton-proton correlations →

Identification of compounds of biological significance in foodstuffs by LC-NMR/MS. Olive oil

Methods & Applications, ,

There is a great interest in understanding the biochemical basis for the reported beneficial health effects of particular diets or food groups. Characterising the wide variety of nutrients in the things we eat and drink in detail is a substantial analytical challenge, especially when numerous sets of molecules in such mixtures may have very similar chemical structures.

Continue reading Identification of compounds of biological significance in foodstuffs by LC-NMR/MS. Olive oil →

A new way to measure small proton-carbon coupling constants

Methods & Applications, Our Publications, , ,

About this Journal“IPAP–HSQMBC: Measurement of long-range heteronuclear coupling constants from spin-state selective multiplets”, by Sergi Gil, Juan Félix Espinosa and Teodor Parella; Journal of Magnetic Resonance, 207, 312-321 (2010). DOI: 10.1016/j.jmr.2010.09.017

A new NMR approach is proposed for the measurement of long-range heteronuclear coupling constants (nJXH,n > 1) in natural abundance molecules. Two complementary in-phase (IP) and anti-phase (AP) data are separately recorded from a modified HSQMBC experiment and then added/subtracted to provide spin-state-selective α/β–HSQMBC spectra. Continue reading A new way to measure small proton-carbon coupling constants →