Dr. Teodor Parella, Director of the NMR Service and Associate Professor in the Chemistry Department at Universitat Autònoma de Barcelona, received last September the GERMN-Bruker Award at the VI GERMN Bienal Meeting held in Aveiro, Portugal, for his contributions to the development and application of the NMR spectroscopy technique. Continue reading Teodor Parella, SeRMN Director, receives GERMN-Bruker NMR Award
Next week several SeRMN members will present our research work at the IV Ibero-American NMR – VI GERMN Bienal – III Iberian NMR joint meeting that will take place in Aveiro (Portugal) from 25th to 28th September. Find below a summary of our contributions.
“Accurate measurement of small heteronuclear coupling constants from pure-phase α/β HSQMBC”, by Sergi Gil, Juan Félix Espinosa and Teodor Parella; Journal of Magnetic Resonance 213, 1, 145-150 (2011). DOI:10.1016/j.jmr.2011.09.036
A simple proton-selective α/β-HSQMBC experiment is proposed for the accurate measurement of long-range proton–carbon coupling constants (nJCH) in small molecules without need for an individualized and time-consuming post-processing fitting procedure. Continue reading Accurate measurement of small heteronuclear coupling constants from pure-phase α/β HSQMBC cross-peaks
“A definitive NMR solution for the simple and accurate measurement of the magnitude and the sign of small heteronuclear coupling constants on protonated and non-protonated carbons”, by Josep Saurí, Juan Félix Espinosa and Teodor Parella; Angew. Chem. Int. Ed. (2012) DOI: 10.1002/anie.201108959
The measurement of long-range proton carbon coupling constants in natural-abundance molecules has always been a tranding topic for the NMR community. Despite the extensive number of NMR techniques that have been developed, there are still remain two unsolved problems pertaining to non-protonated carbons, namely, a) and accurate measurement of very small coupling constants (less than 2-3 Hz) , and b) the absence of a general and robust approach to determine the sign of the coupling. Continue reading Measurement of the magnitude and the sign of small nJCH on protonated and non-protonated carbons
“Selective 1D HCH experiment: a fast NMR tool that connect protons belonging to different spin systems”, by Sergi Gil, Juan Félix Espinosa and Teodor Parella; Magnetic Resonance in Chemistry 49, 301-306 (2011). DOI: 10.1002/mrc.2744
A selective 1D version of the HCH experiment (selHCH) is proposed for the efficient and fast correlation between protons belonging to different spin systems. The experiment consists of two consecutive, doubly selective heteronuclear JCH transfer steps that can individually be optimized. As any conventional proton-selective 1D experiment, the successful application of a frequency-selective 180° pulse on a well-isolated proton is the only practical requirement. Continue reading Fast 1D long-range proton-proton correlations
New NMR Books (2)
NMR Studies of Translational Motion: Principles and Applications – Hardcover, Cambridge University Press (August 31, 2009) by W.S. Price
Ligand-macromolecular Interactions in Drug Discovery: Methods and Protocols – Hardcover, Humana Press (March 23, 2010) by A.C.A. Roque
Practical Small Animal MRI – Hardcover, Wiley-Blackwell; 1 edition (July 21, 2009) by P.R. Gavin
Modelling 1H NMR Spectra of Organic Compounds: Theory, Applications and NMR Prediction Software – Hardcover, Wiley (December 23, 2008) by R. Abraham
Single-Sided NMR – Hardcover (Jan. 28, 2011) by Federico Casanova, Juan Perlo and Bernhard Blümich.
Pocket Guide to Biomolecular NMR by Michaeleen Doucleff, Mary Hatcher-Skeers and Nicole J. Crane (Mar 9, 2011).
Essential Practical NMR for Organic Chemistry by Stephen Richards and John Hollerton (Feb 15, 2011)
Magnetic Resonance Microscopy: Spatially Resolved NMR Techniques and Applications by Sarah Codd and Joseph D. Seymour (Feb 4, 2009)
The SMASH 2011 NMR Meeting will be held at Le Majestic Centre de Congrès in Chamonix, France from September 18th through September 21st. I’ll go there. More info here.
IX Curso Avanzado de RMN
12-17 June (2011) in Jaca(Huesca).
I will give the lecture “Pulsed Field Gradients: Coherence Transfer Pathways Selection”
“IPAP–HSQMBC: Measurement of long-range heteronuclear coupling constants from spin-state selective multiplets”, by Sergi Gil, Juan Félix Espinosa and Teodor Parella; Journal of Magnetic Resonance, 207, 312-321 (2010). DOI: 10.1016/j.jmr.2010.09.017
A new NMR approach is proposed for the measurement of long-range heteronuclear coupling constants (nJXH,n > 1) in natural abundance molecules. Two complementary in-phase (IP) and anti-phase (AP) data are separately recorded from a modified HSQMBC experiment and then added/subtracted to provide spin-state-selective α/β–HSQMBC spectra. Continue reading A new way to measure small proton-carbon coupling constants