Tag Archives: E.COSY

PhD Thesis: Modern NMR Methodologies for the Measurement of Homo- and Heteronuclear Coupling Constants in Small Molecules

Last 21st May 2014 I defended my PhD Thesis entitled: Modern NMR Methodologies for the Measurement of Homo- and Heteronuclear Coupling Constants in Small Molecules

 

PhD thesis JSauri - Graphical Abstract - Publications

 

The dissertation is focused on the development of modern NMR methodologies for the measurement of homo- and heteronuclear coupling constants in small molecules, and is presented as a compendium of eight (8) publications that have been published in several peer-reviewed journals as original research papers.  Continue reading PhD Thesis: Modern NMR Methodologies for the Measurement of Homo- and Heteronuclear Coupling Constants in Small Molecules

Easy measurement of one-bond proton-carbon and geminal proton-proton coupling constants in diastereotopic methylene groups

Straightforward measurement of individual 1J(CH) and 2J(HH) in diastereotopic CH2 groups” by Josep Saurí, Laura CastañarPau Nolis, Albert Virgili and Teodor ParellaJournal of Magnetic Resonance 242 (2014) 33–40DOI: 10.1016/j.jmr.2014.02.003

The C-HA cross-peak corresponding to a diastereotopic CHAHB methylene spin system exhibits a characteristic 1:0:1 multiplet pattern along the indirect dimension of a ω1-coupled HSQC spectrum. Continue reading Easy measurement of one-bond proton-carbon and geminal proton-proton coupling constants in diastereotopic methylene groups

J-selHSQMBC: Simultaneous measurement of JHH and two different nJCH using IPAP, J-resolved and E.COSY principles

cover_MRC“Simultaneous measurement of J(HH) and two different nJ(CH) coupling constants from a single multiply-edited 2D cross-peak”, by Josep Saurí and Teodor ParellaMagn. Reson. Chem. 201351, 397-402. DOI: 10.1002/mrc.3960

Three different J-editing methods (IPAP, E.COSY and J-resolved) are implemented in a single NMR experiment to provide spin-state-edited 2D cross-peaks from which simultaneous measurement of different homonuclear and heteronuclear coupling constants can be performed. Continue reading J-selHSQMBC: Simultaneous measurement of JHH and two different nJCH using IPAP, J-resolved and E.COSY principles

P.E.HSQMBC: Simultaneous measurement of proton–proton and proton–carbon coupling constants

“P.E.HSQMBC: Simultaneous measurement of proton–proton and proton–carbon coupling constants” by Josep Saurí, Pau Nolis, Laura Castañar, Albert Virgili and Teodor Parella. Journal of Magnetic Resonance 224 (2012) 101–106. DOI: 10.1016/j.jmr.2012.09.007

A long-range optimized P.E.HSQC experiment, named P.E.HSQMBC, is proposed for the simultaneous measurement of a complete set of homonuclear and heteronuclear coupling constants from a single 2D cross-peak. Continue reading P.E.HSQMBC: Simultaneous measurement of proton–proton and proton–carbon coupling constants