Simultaneous multi-slice excitation in spatially encoded NMR experiments

SeRMN seminar

  • Date:  Thursday 5th September, 2013
  • Hour: 10 am
  • Location:  SeRMN,  Facultats de Ciències i Biociències, C2/-135
  • Speaker:  Laura Castañar, SeRMN PhD Student & Teaching Assistant, Dept. of Chemistry.

multiple-slice

Simultaneous multi-slice excitation in spatially encoded NMR experiments

A novel strategy to enhance the experimental sensitivity in spatially encoded NMRexperiments is presented. The use of a multiple-frequency modulated pulse applied simultaneously to an encoding gradient can afford a substantial sensitivity gain with respect to single-slice selected experiments. The z-dependent position of each individual proton resonance allows the choice of a determined number of complementary k offsets that allows parallel data collection for a specific proton in multiple parts of the NMR tube whereas other mutually J-coupled protons are not excited into the same slice. The experimental set-up protocol to fulfill the sampled frequency requirement is simple and the results can be inmediately adapted to a wide range of applications.

Reference:

 “Simultaneous multi-slice excitation in Spatially encoded NMR experiments” by Laura Castañar, Pau Nolis, Albert Virgili and Teodor Parella. Chem. Eur. J. 2013, 19, 15472–1547. DOI: https://dx.doi.org/10.1002/chem.201303272