- Date: Thursday 5th September, 2013
- Hour: 10 am
- Location: SeRMN, Facultats de Ciències i Biociències, C2/-135
- Speaker: Laura Castañar, SeRMN PhD Student & Teaching Assistant, Dept. of Chemistry.
Simultaneous multi-slice excitation in spatially encoded NMR experiments
A novel strategy to enhance the experimental sensitivity in spatially encoded NMRexperiments is presented. The use of a multiple-frequency modulated pulse applied simultaneously to an encoding gradient can afford a substantial sensitivity gain with respect to single-slice selected experiments. The z-dependent position of each individual proton resonance allows the choice of a determined number of complementary k offsets that allows parallel data collection for a specific proton in multiple parts of the NMR tube whereas other mutually J-coupled protons are not excited into the same slice. The experimental set-up protocol to fulfill the sampled frequency requirement is simple and the results can be inmediately adapted to a wide range of applications.
“Simultaneous multi-slice excitation in Spatially encoded NMR experiments” by Laura Castañar, Pau Nolis, Albert Virgili and Teodor Parella. Chem. Eur. J. 2013, 19, 15472–1547. DOI: https://dx.doi.org/10.1002/chem.201303272