“In Vivo Assessment of Neurodegeneration in Niemann-Pick Type C Mice by Quantitative T2 Mapping and Diffusion Tensor Imaging”, by John W. Totenhagen, Silvia Lope-Piedrafita, Ivan A. Borbon, Eriko S. Yoshimaru, Robert P. Erickson, and Theodore P. Trouard; Journal of Magnetic Resonance Imaging 35 (2012), 528-536. doi: 10.1002/jmri.22837

NIEMANN-PICK TYPE C (NPC) disease is a rare genetic neurodegenerative disease with no cure and few effective options for treatment. Diagnosis is most often made during childhood with symptoms progressively worsening and leading to death prior to adulthood. Continue reading Neurodegeneration in NPC Mice by T₂ and DTI MRI →