Marcó, Núria, Roberto R. Gil & Teodor Parella. 2018. Isotropic/Anisotropic NMR Editing by Resolution-Enhanced NMR Spectroscopy. ChemPhysChem 19(9). 1024–1029. DOI: 10.1002/cphc.201800094

Modern resolution-enhanced NMR techniques can monitor the in-situ discrimination of co-existing isotropic and anisotropic contributions of small molecules dissolved in weakly aligning PMMA/CDCl3 media. The simultaneous sign-sensitive determination of accurate Δδ(¹H) and Δδ(¹³C) between isotropic and anisotropic signals,  and/or  ¹T_CH and ¹J_CH coupling constants (and consequently 1H-13C RDCs and 1H/13C RCSAs) can be performed from spectral-aliased HSQC spectra.

Pulse Programs Code for Bruker:

• PIP HSQC