Tag Archives: SAPS-HSQC

SeRMN at the SMASH NMR 2015 Conference

2015-09-30NMR Events & Courses, Our ResearchHSQMBC, HSQMBC-TOCSY, LR-HSQMBC, SAPS-HSQCNúria

Some of our last research works has been presented by Núria Marcó at the annual meeting of the SmallMolecule NMR Conference (SMASH) that has been taken place in Baveno (Italy) from 20^thto 24^thSeptember 2015.

Find below a summary of our contributions.

Continue reading SeRMN at the SMASH NMR 2015 Conference →

PhD Thesis: Development and application of modern pure shift NMR techniques and improved HSQC and HSQMBC experiments

2015-07-27Methods & Applications, News from the SeRMN, Our Researchcoupling-constants, enhanced resolution, full sensitivity, HOBS, homonuclear decoupling, HSQC, HSQMBC, perfect HSQC, PhD Thesis, PIP experiments, pure in-phase signals, pure-shift NMR, residual dipolar couplings, SAPS-HSQC, sensitivity enhancementLaura

Last 16^st July 2015 I defended my PhD Thesis entitled: Development and application of modern pure shift NMR techniques and improved HSQC/HSQMBC experiments.

The present doctoral thesis is framed within the Nuclear Magnetic Resonance (NMR) spectroscopy field, more specifically in the design of modern NMR methodologies. The research work carried out is focused on the design and application of new and modern NMR methodologies (i) to perform efficient broadband ¹H homodecoupling in 1D/2D NMR experiments and (ii) to accurately determine homo- and heteronuclear coupling constants in isotropic and anisotropic conditions through improved HSQC and HSQMBC-type experiments. The thesis is presented as a compendium ten (10) publications that have been published in several peer-reviewed international scientific journals as original research papers. Continue reading PhD Thesis: Development and application of modern pure shift NMR techniques and improved HSQC and HSQMBC experiments →

PhD Thesis by Laura Castañar: Pulse Programs and Data Set Examples

2015-05-31Methods & Applications, News from the SeRMN, NMR Events & Courses, Our Publications, Our Researchaligned-media, coupling-constants, enantiodifferentiation, enhanced resolution, full sensitivity, heteronulear coupling constants, HOBS, HOBS-HSQC, HOBS-HSQC-TOCSY, HOBS-HSQMBC, HOBS-TOCSY, homodecoupling, homonuclear decoupling, HSQC, HSQMBC, J-resolved, multi-slice selection, multiple frequency pulses, NUS, one-bond proton-carbon coupling constants, perfect HSQC, PhD Thesis, PIP experiments, proton-carbon coupling constants, proton-proton coupling constants, pure in-phase signals, Pure shift, quantitative nmr, RDCs, Relaxation times, residual dipolar couplings, resolution enhancement, SAPS-HSQC, sensitivity enhancement, sign of coupling constants, spectral aliasing, T1-relaxation, T2-relaxation, two-bonds proton-proton coupling constantsLaura

Development and application of modern pure shift NMR techniques and improved HSQC/HSQMBC experiments

In the following links one can find Data Set Examples of each Publication presented in the Thesis Work, as well as the corresponding Pulse Program Code for Bruker. All 2D spectra have been previously phased and 2ii, 2ir, and 2ri files removed, otherwise data sets would be too big. Continue reading PhD Thesis by Laura Castañar: Pulse Programs and Data Set Examples →

Review – Pure shift NMR experiments: recent developments, methods and applications

2015-05-02Methods & Applications, NMR Bibliography, Our Publications, Our Researchenantiodifferentiation, enhanced resolution, full sensitivity, heteronulear coupling constants, HOBS, HOBS-HSQC, HOBS-HSQMBC, HOBS-TOCSY, homodecoupling, homonuclear decoupling, Pure shift, Relaxation times, resolution enhancement, review, SAPS-HSQC, sensitivity enhancement, T1-relaxation, T2-relaxationLaura

“Broadband ¹H homodecoupled NMR experiments: recent developments, methods and applications” by Laura Castañar and Teodor Parella. Magnetic Resonance in Chemistry, 2015. DOI: 10.1002/mrc.4238

In recent years, a great interest in the development of new broadband ¹H homonuclear decoupled techniques providing simplified J_HH multiplet patterns has emerged again in the field of small molecule NMR. The resulting highly resolved ¹H NMR spectra display resonances as collapsed singlets, therefore minimizing signal overlap and expediting spectral analysis. This review aims at presenting the most recent advances in pure shift NMR spectroscopy, with a particular emphasis to the Zangger–Sterk experiment. Continue reading Review – Pure shift NMR experiments: recent developments, methods and applications →

Review: Recent Advances in Small Molecule NMR: Improved HSQC and HSQMBC Experiments

2015-03-02Methods & Applications, NMR Bibliography, Our Publications, Our ResearchHOBS-HSQC, HOBS-HSQMBC, HSQC, HSQMBC, IPAP, nmr, one-bond proton-carbon coupling constants, perfect HSQC, PIP experiments, proton-carbon coupling constants, pure-shift NMR, quantitative nmr, SAPS-HSQCLaura

“Recent Advances in Small Molecule NMR: Improved HSQC and HSQMBC Experiments” by Laura Castañar and Teodor Parella. Annual Reports on NMR Spectroscopy, 2015, 84:163–232. DOI: 10.1016/bs.arnmr.2014.10.004

A general description of the latest developments in heteronuclear single-quantum correlation and heteronuclear single-quantum multiple bond correlation experiments designed for small molecules at the natural isotopic abundance is reported. Continue reading Review: Recent Advances in Small Molecule NMR: Improved HSQC and HSQMBC Experiments →

SeRMN – NMR Service at UAB

Research & development, training, and facility management