Tag Archives: nanotechnology

Novel MRI contrast agents: peptide-SPION conjugates

Journal Cover:Chem. Commun., 2012, 48, 5322-5324“Efficient γ-amino-proline-derived cell penetrating peptide-superparamagnetic iron oxide nanoparticle conjugates via aniline-catalyzed oxime chemistry as bimodal imaging nanoagents”, by Cavalli S, Carbajo D, Acosta M, Lope-Piedrafita S, Candiota AP, Arús C, Royo M, Albericio F; Chem. Commun 48 (2012) p. 5322. DOI: 10.1039/C2CC17937G

Recent advances in nanotechnology have offered new opportunities for detection, prevention, and treatment of different diseases. In this respect engineered superparamagnetic iron oxide nanoparticles (SPIONs) represent an advanced tool in nanomedicine because they can be loaded in a multiple and orthogonal way with drugs and probes in order to simultaneously act as molecular imaging agents and drug carriers. Continue reading Novel MRI contrast agents: peptide-SPION conjugates